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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMK4 All Species: 9.09
Human Site: S43 Identified Species: 16.67
UniProt: Q16566 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q16566 NP_001735.1 473 51926 S43 G S N R D A L S D F F E V E S
Chimpanzee Pan troglodytes XP_517873 603 65471 S173 G S N R D A L S D F F E V E S
Rhesus Macaque Macaca mulatta XP_001101268 613 65896 S183 G S N R D A L S D F F E V E S
Dog Lupus familis XP_541780 370 41140 F31 D V L G T G A F S E V I L A E
Cat Felis silvestris
Mouse Mus musculus P08414 469 52609 E43 D P L G D F F E V E S E L G R
Rat Rattus norvegicus P13234 474 53133 E43 D P L S D F F E V E S E L G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513096 402 44436 E43 D T L A H Y F E V E S E L G R
Chicken Gallus gallus Q5ZKI0 479 54184 E59 A R D H Q K L E R E A R I C R
Frog Xenopus laevis Q9DG02 475 53914 E58 A R D H Q K L E R E A K I C R
Zebra Danio Brachydanio rerio NP_001017607 364 40603 L25 D G S K K E T L A D F Y E L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 E83 L H D S I Q E E N Y H Y L V F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797065 374 40935 A35 G M K V S H I A E F E S L F T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZSA2 531 59876 G83 I R K F Y S L G K E L G R G Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.2 73.2 34 N.A. 80.3 79.9 N.A. 70.1 34.4 33.6 65.3 N.A. 30.3 N.A. N.A. 40.3
Protein Similarity: 100 78.4 74.8 49.6 N.A. 85.6 86.5 N.A. 78 53.8 52.2 72.3 N.A. 49.8 N.A. N.A. 56.2
P-Site Identity: 100 100 100 0 N.A. 13.3 13.3 N.A. 6.6 6.6 6.6 6.6 N.A. 0 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 6.6 N.A. 20 20 N.A. 20 20 26.6 20 N.A. 26.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 32.2 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 8 0 24 8 8 8 0 16 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % C
% Asp: 39 0 24 0 39 0 0 0 24 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 8 8 47 8 54 8 47 8 24 16 % E
% Phe: 0 0 0 8 0 16 24 8 0 31 31 0 0 8 8 % F
% Gly: 31 8 0 16 0 8 0 8 0 0 0 8 0 31 0 % G
% His: 0 8 0 16 8 8 0 0 0 0 8 0 0 0 0 % H
% Ile: 8 0 0 0 8 0 8 0 0 0 0 8 16 0 0 % I
% Lys: 0 0 16 8 8 16 0 0 8 0 0 8 0 0 0 % K
% Leu: 8 0 31 0 0 0 47 8 0 0 8 0 47 8 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 24 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 16 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 16 8 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 24 0 24 0 0 0 0 16 0 0 8 8 0 39 % R
% Ser: 0 24 8 16 8 8 0 24 8 0 24 8 0 0 24 % S
% Thr: 0 8 0 0 8 0 8 0 0 0 0 0 0 0 8 % T
% Val: 0 8 0 8 0 0 0 0 24 0 8 0 24 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 8 0 0 0 8 0 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _